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Hiroyuki Hamakawa Selected Research

Salivary Gland Neoplasms (Salivary Gland Cancer)

2/2009CD151 regulates HGF-stimulated morphogenesis of human breast cancer cells.
6/2008Basic evidence of molecular targeted therapy for oral cancer and salivary gland cancer.
5/2008Role of Akt isoforms in HGF-induced invasive growth of human salivary gland cancer cells.
7/2006Hypoxia enhances c-Met/HGF receptor expression and signaling by activating HIF-1alpha in human salivary gland cancer cells.
12/2003Thiazolidinediones inhibit cell growth of human oral squamous cell carcinoma in vitro independent of peroxisome proliferator-activated receptor gamma.
3/2002Expression of peroxisome proliferator-activated receptor gamma and the growth inhibitory effect of its synthetic ligands in human salivary gland cancer cell lines.

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Hiroyuki Hamakawa Research Topics

Disease

42Neoplasms (Cancer)
10/2016 - 03/2002
29Squamous Cell Carcinoma of Head and Neck
01/2018 - 06/2002
15Mouth Neoplasms (Oral Cancer)
12/2017 - 06/2002
10Lymphatic Metastasis
01/2016 - 10/2002
7Carcinoma (Carcinomatosis)
03/2013 - 03/2002
6Salivary Gland Neoplasms (Salivary Gland Cancer)
02/2009 - 03/2002
4Breast Neoplasms (Breast Cancer)
01/2011 - 11/2004
4Prostatic Neoplasms (Prostate Cancer)
08/2010 - 08/2004
3Head and Neck Neoplasms (Head and Neck Cancer)
08/2012 - 10/2003
3Neoplasm Metastasis (Metastasis)
01/2011 - 11/2003
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
06/2010 - 10/2002
1Disease Progression
01/2018
1Nausea
12/2017
1Vomiting
12/2017
1Hyperglycemia
01/2015
1Prediabetic State (Prediabetes)
01/2015
1Periodontitis
01/2015
1Oncogene Addiction
06/2013
1Acinar Cell Carcinoma
09/2011
1Mucoepidermoid Carcinoma
09/2011
1Adenoma (Adenomas)
09/2011
1Adenolymphoma
09/2011
1Virus Diseases (Viral Diseases)
03/2011
1Adenoid Cystic Carcinoma (Cylindroma)
05/2008

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
10/2016 - 03/2002
7Messenger RNA (mRNA)IBA
01/2016 - 03/2002
5Gefitinib (Iressa)FDA Link
06/2008 - 10/2003
5ErbB Receptors (EGF Receptor)IBA
01/2004 - 09/2003
4LigandsIBA
08/2012 - 03/2002
4Tyrosine Kinase InhibitorsIBA
01/2004 - 10/2003
3DNA (Deoxyribonucleic Acid)IBA
07/2011 - 10/2003
3Protein Isoforms (Isoforms)IBA
08/2010 - 04/2004
3Androgen Receptors (Androgen Receptor)IBA
08/2010 - 09/2006
3squamous cell carcinoma-related antigenIBA
06/2010 - 09/2003
3AndrogensIBA
01/2010 - 08/2004
3PPAR gammaIBA
06/2008 - 03/2002
3Green Fluorescent ProteinsIBA
05/2008 - 10/2002
3Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
05/2008 - 08/2004
3ChemokinesIBA
01/2006 - 11/2003
2Progesterone Receptors (Progesterone Receptor)IBA
10/2016 - 11/2004
2ProgesteroneFDA LinkGeneric
10/2016 - 11/2004
2atelocollagenIBA
10/2015 - 08/2010
2Fluorouracil (Carac)FDA LinkGeneric
07/2013 - 06/2002
2PicibanilIBA
07/2013 - 08/2012
2Vascular Endothelial Growth Factor CIBA
01/2011 - 01/2004
2Gonadal Steroid Hormones (Sex Hormones)IBA
01/2011 - 11/2004
2Small Interfering RNA (siRNA)IBA
01/2010 - 10/2008
2Chemokine ReceptorsIBA
03/2009 - 01/2006
2Proto-Oncogene Proteins c-metIBA
07/2006 - 08/2004
2titanium silicide (TS-1)IBA
02/2004 - 09/2003
2Cisplatin (Platino)FDA LinkGeneric
12/2003 - 06/2002
2Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2003 - 01/2003
1PlatinumIBA
01/2018
1Cetuximab (Erbitux)FDA Link
01/2018
1Palonosetron (Aloxi)FDA Link
12/2017
1Interleukin-6 (Interleukin 6)IBA
12/2017
1AnnexinsIBA
01/2016
1Keratin-19 (Keratin 19)IBA
01/2016
1Dental Implants (Dental Implant)IBA
12/2015
1InterferonsIBA
10/2015
1ribonucleotide reductase M2IBA
05/2015
1Blood Glucose (Blood Sugar)IBA
01/2015
1Interleukin-8 (Interleukin 8)IBA
01/2014
1InterleukinsIBA
01/2014
1Aurora Kinase AIBA
06/2013
1MLN 8237IBA
06/2013
1Basic Helix-Loop-Helix Transcription FactorsIBA
03/2013
1Nucleic AcidsIBA
10/2012
1Toll-Like Receptor 4IBA
08/2012
1Immunologic Adjuvants (Immunologic Adjuvant)IBA
08/2012
1LipopolysaccharidesIBA
08/2012
1Caspase 1 (ICE Protease)IBA
08/2012
1Mitogen-Activated Protein KinasesIBA
08/2012
1Phosphopyruvate Hydratase (Enolase)IBA
01/2012
1VimentinIBA
01/2012
1von Willebrand FactorIBA
01/2012
1S100 Proteins (S 100 Protein)IBA
01/2012
1Membrane Proteins (Integral Membrane Proteins)IBA
09/2011
1CateninsIBA
09/2011
1Telomerase (Telomerase Reverse Transcriptase)IBA
09/2011
1Cadherins (E-Cadherin)IBA
09/2011
1Neutralizing AntibodiesIBA
03/2011
1Hormones (Hormone)IBA
01/2011
1Biological ProductsIBA
01/2011
1LuciferasesIBA
06/2010
1VA 061 (VA061)IBA
01/2010
1Oxygen (Dioxygen)IBA
03/2009
1Integrin alpha3IBA
02/2009
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2008
1AutoantibodiesIBA
04/2008

Therapy/Procedure

9Therapeutics
01/2016 - 02/2004
7Radiotherapy
07/2013 - 06/2002
4Drug Therapy (Chemotherapy)
01/2018 - 06/2002
4Chemoradiotherapy
09/2011 - 06/2002
2Oral Surgery (Maxillofacial Surgery)
08/2015 - 06/2002
2Molecular Targeted Therapy
06/2013 - 06/2008
2Neoadjuvant Therapy
12/2003 - 06/2002
1Overlay Denture
02/2016
1Bone-Anchored Prosthesis
02/2016
1Neck Dissection (Radical Neck Dissection)
01/2016